Phenylephrine reddit

tl;dr: It makes your blood vessels to constrict which allow less fluid to leave the blood vessels and enter the nose, throat and sinus linings, which results in decreased inflammation of nasal membranes as well as decreased mucus production. Thus, by constriction of blood vessels, mainly those located in the nasal passages, …

Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist.Phenylephrine nasal spray has the same 3 day use limit; and oral phenylephrine is trash. I would never recommend it. If symptoms persist beyond 3 days I’d recommend seeing a physician anyway; but they can have some pseudoephedrine in the mean time. But honestly; I’m pretty sure rebound congestion from oxymetazoline is a myth.2 great_site_not • 5 yr. ago You need different friends. 200mg of phenylephrine is extremely dangerous, and anyone who'd hand it to you and tell you it's fine is dangerously negligent (assuming it wasn't malicious).Evidence of phenylephrine's effectiveness comes from a review that combined and analyzed the results of seven individual studies. It found the drug had a small but real effect on nasal airway ... But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ephedrine and pseudoephedrine (which you need to purchase from behind the ...According to Wikipedia: "Methcathinone production utilizes the oxidation of pseudoephedrine or ephedrine, the former being preferred because of much higher yields achieved. Oxidation of pseudoephedrine to methcathinone requires little chemistry experience, making it (relatively) easy to synthesize. [5] [unreliable source?]

This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment. Like super fast heart rate, shaky, sweaty,anxiety, kinda dizzy. Feels like I did a fat line of bad coke. I am not a rookie or a light weight and I take actual stimulants often. I just had no idea a decongestant could make me feel like this. Is that normal?Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist.Phenylephrine comes as a 0.125%, 0.25%, 0.5%, and 1% solution (liquid) to spray into the nose. It is usually used as needed, not more than every 4 hours. The 0.5% and 1% solutions may be used in adults and children 12 years of age and older. The 0.25% solution may be used in children 6 to 12 years of age.Dilated blood vessels can cause nasal congestion (stuffy nose). Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Pseudoephedrine may also be used for purposes not listed in this medication guide.

Phenylephrine. Sections; Download Chapter PDF; Share. Email; Twitter; Facebook; Linkedin; Reddit. Get Citation. Citation. Disclaimer: These citations have been ...When Sudafed (the OG Sudafed with pseudoephedrine) was taken off of the regular OTC shelves and moved behind the pharmacy counter Sudafed PE (the one that’s just phenylephrine) was used to fill the empty space on the store shelves and less savvy consumer bought it, thinking “Sudafed is sudafed” … and phenylephrine IS an effective ... 5 août 2022 ... Decongestants, such as pseudoephedrine and phenylephrine, temporarily relieve the stuffy nose of allergies. Decongestants are found in many ...Sep 12, 2023 · On Tuesday, Sept. 12, 2023 advisers to the Food and Drug Administration said that a different ingredient, phenylephrine, is ineffective at relieving nasal congestion. Drugmakers reformulated their products with phenylephrine after a 2006 law required pseudoephedrine-containing medications be sold from the behind pharmacy counter. Confusingly, popular cold remedy Sudafed – which takes its name from pseudoephedrine – now comes in two forms: a shop version, containing phenylephrine, and a behind-the-counter ...

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Will Phenylephrine get me high? I have a bunch of Phenylephrine and I was wondering if I took this I would feel anything I have abt 34 pills and I just wanted to know if this stuff would get me high or not? This thread is archived New comments cannot be posted and votes cannot be cast 3 13 comments Best Top New Controversial Q&A Dissolve either reds or whites in water. Distilled water is best, but even tap water should work. About a quart for every 3-5 grams of PSE. Whites have to be boiled for best results, reds don't. Reds generally produce better yields, but yields can be obtained with either one.By 2022, the FDA estimates that Americans bought 242 million phenylephrine-containing products, taking the lion's share of the decongestant market and generating nearly $1.8 billion in sales.Examples of commonly used decongestants include phenylephrine and pseudoephedrine.Often these ingredients are included in multisystem cold and flu preparations. Due to the nature of medications, it is important to always read label ingredients for medications and warnings on boxes to know what you are taking and …Phenylephrine is a type of nasal decongestant in over-the-counter (OTC) medications, such as Sudafed PE. Phenylephrine is available as a standalone …

I personally think phenylephrine is a placebo. So many people don't know any better and just keep taking Sudafed because "that's what you take" and don't even think to look at that. But it's literally never done anything for me.2 ks99 • 10 yr. ago It is not a mystery chemical, it is used as a decongestant that has largely replaced pseudoephedrine in OTC medications (pseudo is behind the counter where I'm from). I would not take anything that didn't have only DXM in though as well.Phenylephrine is a vasoconstrictor - which reduces sinus congestion by shrinking capillaries and veins. Also, from Wikipedia: Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo for allergy relief.The Acetaminophen could harm your liver depending on what dose you end up taking. Phenylephrine even at doses slightly higher than normal can end up with a rapid heartbeat/High blood pressure/anxiety/etc. Please just go back to the store and buy a brand that just has Dextromethorphan in it. Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients. Phenylephrine — the ingredient deemed ineffective — took off in popularity as a replacement for pseudoephedrine. Mike Koelzer, a pharmacist in Grand Rapids, Michigan, said he doesn't expect any...14 déc. 2021 ... Dans un contexte chirurgical ophtalmologique, la phényléphrine par voie locale (Instillation oculaire de gouttes) est un médicament couramment ...Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist.Horak et al 2008, Day et al and a half dozen others found Phenylephrine significantly less effective than pseudoephedrine as decongestant. As far as I know every trial comparing the pseudoephedrine and phenylephrine as a decongestant has found pseudoephedrine superior, in most cases by a large margin. I personally think phenylephrine is a placebo. So many people don't know any better and just keep taking Sudafed because "that's what you take" and don't even think to look at that. But it's literally never done anything for me.

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By 2022, the FDA estimates that Americans bought 242 million phenylephrine-containing products, taking the lion's share of the decongestant market and generating nearly $1.8 billion in sales.Other pharmacists have expressed concerns over phenylephrine's effectiveness as a nasal decongestant,[1] and other clinicians have indicated concern for regulatory actions that reduced the availability of pseudoephedrine.[12][13] A subsequent meta-analysis by the same researchers concluded that there is insufficient evidence for its ...A key ingredient in many over-the-counter cold and allergy medications called phenylephrine doesn’t work to get rid of nasal congestion, a Food and Drug Administration advisory panel concluded ...tl;dr: It makes your blood vessels to constrict which allow less fluid to leave the blood vessels and enter the nose, throat and sinus linings, which results in decreased inflammation of nasal membranes as well as decreased mucus production. Thus, by constriction of blood vessels, mainly those located in the nasal passages, …The amount of fluids infused during the study period in the phenylephrine and norepinephrine groups was similar (2,554 ± 1,140 ml versus 2,431 ± 1,010 ml, P = 0.751). Phenylephrine dosages were higher than those for norepinephrine 12 hours after randomization (P < 0.001) (Figure (Figure2). 2). The goal MAP of 65 to 75 mmHg was …Sep 12, 2023 · Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating alpha-1 adrenergic receptors in the ... Brompheniramine And Phenylephrine (Rynex PE) received an overall rating of 0 out of 10 stars from 0 reviews. See what others have said about Brompheniramine And Phenylephrine (Rynex PE), including the effectiveness, ease of use and side eff...

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Pseudoephedrine is fine. The one you gotta look out for is phenylephrine, AKA Sudafed-PE. It reacts with amphetamine-related drugs, including Adderall and meth, to cause heart problems. Always, always look up drug interactions when you're on something long-term! Interactions aren't always major or dangerous, but it's good to know about them. 7 sept. 2023 ... ... phenylephrine ophthalmic spray for mydriasis) and developing the ... Share on Reddit · Share by Mail. https://eyenovia.com/wp-content/uploads ...It just causes more nausea in my experience, not really dangerous. thats not too bad, if you dont mind some nausea. for a 240mg dose thats 3.2g, which could certainly upset a weak stomach. if it did cause any problems you would be fine within an hour tops to enjoy your trip fully. Thanks for reply.so i have a bunch of phenylephrine hydrochloride from pills they only contain 500mg of panadol and 5mg of phenylephrine hydrochloride each and there's 20 tablets per box if 3 friends got 3 boxes and we extracted the phenylephrine hydrochloride we'd have around 300mg give or take because we're using a sketchy homemade chemistry setup rather …Take a syringe and draw up 1 ml of phenylephrine from the vial (vial concentration must be 10 mg/ml) Inject this into a 100 ml bag of NS. Now you have 100 mls of phenylephrine 100 mcg/ml. Draw up some into a syringe; each ml in the syringe is 100 mcg. Dose: 0.5-2 ml every 1-5 minutes (50-200 mcg) No extravasation worries! Mixing …Currently about 5 weeks in on 10 mg. I got a sinus infection, was wondering if anybody knows good cold medicine that's safe to take. Specifically I have tylenol sinus and headache which has Phenylephrine HCI in it. A brief search I couldn't find anything about interactions but figured I would see if anybody here had some info. Concerta is a prescription drug used for ADHD. Find out about possible interactions with alcohol, other drugs, supplements, foods, and more.I suffer from hay fever during summer and usually take piriton tablets as they seem to work best for me, but I can't tell if I'm allowed to bring them to Japan. I understand certain medication is banned and some other types of antihistamines are allowed, but cannot find a definitive answer regarding chlorphenamine maleate on the internet.4 oct. 2023 ... ... Reddit Print Story Like. An advisory panel to the Food and Drug ... phenylephrine doesn't work to clear nasal congestion when taken orally.Evidence of phenylephrine's effectiveness comes from a review that combined and analyzed the results of seven individual studies. It found the drug had a small but real effect on nasal airway ... ….

Research comparing phenylephrine to a placebo in the treatment of nasal congestion has yielded mixed results, with some studies showing minimal effectiveness compared to a placebo. This lack of significant difference in symptom relief has raised questions about the efficacy of phenylephrine in some cases.Here is the complete list of the 344 drug combinations banned from the market by the Centre: • Fixed dose combination of Aceclofenac + Paracetamol + Rabeprazole. • Fixed dose combination of ...Depending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ...On Tuesday, a U.S. Food and Drug Administration advisory committee voted unanimously that the oral formulation of a very common nasal decongestant, phenylephrine, is not effective. The decision ...Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist.Like super fast heart rate, shaky, sweaty,anxiety, kinda dizzy. Feels like I did a fat line of bad coke. I am not a rookie or a light weight and I take actual stimulants often. I just had no idea a decongestant could make me feel like this. Is that normal?Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients.Super interesting article thanks! Epipens stored in EMS vehicles between 1-11 years past expiration only contained up to 31% of original potency. While epipens tested with normal storage up to 90 months past expiration date decreased proportionally with age. Makes me much more careful with epipens -- that's for damn sure! Phenylephrine reddit, 4 comments [deleted] • 5 yr. ago Phenylephrine works as a vasoconstrictor, which raises BP and heart rate. Probably why its associated with an increased risk of …, oral phenylephrine is ineffective as a decongestant, Other examples of scientifically proven ineffective OTC medications include guaifenesin as an expectorant, …, Phenylephrine is an alpha-agonist - that is, it works at "alpha receptors" in our body. The main effects of these receptors is to cause things to squeeze, like blood vessels, for example. That's how they work on congestion - squeezed vessels = less leaky. Phenylephrine mainly works on the alpha-1 receptors, and that's what their job is - squeezing. , Dilated blood vessels can cause nasal congestion (stuffy nose). Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Pseudoephedrine may also be used for purposes not listed in this medication guide., The OTC drug phenylephrine does not work to relieve congestion, an FDA advisory panel said Tuesday. The ingredient is found in a number of cold and allergy pills., Phenylephrine : r/depression • 12 yr. ago by coolgherm Phenylephrine Does anybody know about using phenylephrine as an antidepressant. I have had a cold for the last two weeks and have been taking dayquil to combat the mucus. It has phenylephrine in it. For the last few days of taking it, I have felt better than I have in years., Confusingly, popular cold remedy Sudafed – which takes its name from pseudoephedrine – now comes in two forms: a shop version, containing phenylephrine, and a behind-the-counter ..., Doc Hydramine. The Sudafed PE and all the other Phenylepherine cold remedies are garbage. It was probably pushed through the approval process because they were desperate for a decongestant that you couldn't make meth from. So, they approved something that was not very effective, since there weren't any other options., Phenylephrine will exacerbate the circulatory system effects of dxm and is highly advised against since it's a bad idea to take a bunch of it on its own, much less with a drug which requires great care in selecting combinations because of its wide array of physiological and neurochemical effects. Get something with dxm only and do not take this ..., Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist., This page says: When you bring your personal medicines into Japan up to the amount described below, you do not have to apply for "Yunyu Kakunin-sho", instead the officers at customs check the amount of your bringing medicines, and then you can bring them into Japan. Poison, Deadly poison, Prescription drug : Up to 1 month supply., View community ranking In the Top 1% of largest communities on Reddit. Japanese Throats [serious] ... Acetaminophen 325 mg (Pain reliever/fever reducer) Dextromethorphan HBr 10 mg (Cough suppressant) Phenylephrine HCl 5 mg (Nasal decongestant) Paburon Active Ingredients (per 1.3g pack dose) Ibuprofen 150 mg, Bromohexine hydrochloride 4 mg ..., Gently pat yourself dry with a towel. Fiber supplements. These reduce hemorrhoid bleeding, inflammation, and enlargement by drawing water into your stool to make it easier to pass. A psyllium husk fiber supplement, such as Metamucil or a generic equivalent, is a good choice, although psyllium may cause gas or bloating., View community ranking In the Top 5% of largest communities on Reddit. Phenylephrine Question . Hi all, want to preface my question by saying I'm a new CA1. Yesterday I took over a case where the attending had neo running at 1.5mcg/kg. I've never seen or read information that says to go above 1.0mcg/kg but was wondering why this is?, Over-the-Counter Ocular Decongestants in the United States – Mechanisms ..., 14 déc. 2021 ... Dans un contexte chirurgical ophtalmologique, la phényléphrine par voie locale (Instillation oculaire de gouttes) est un médicament couramment ..., Examples of commonly used decongestants include phenylephrine and pseudoephedrine.Often these ingredients are included in multisystem cold and flu preparations. Due to the nature of medications, it is important to always read label ingredients for medications and warnings on boxes to know what you are taking and …, Phenylephrine is used in a broad array of over-the-counter medications like Sudafed PE and Dimetapp. The drug brought in nearly $1.8 billion in sales in 2022, according to an FDA briefing document ..., Pseudoephedrine is fine. The one you gotta look out for is phenylephrine, AKA Sudafed-PE. It reacts with amphetamine-related drugs, including Adderall and meth, to cause heart problems. Always, always look up drug interactions when you're on something long-term! Interactions aren't always major or dangerous, but it's good to know about them. , Phenylephrine tablet dan sirop. Tujuan: Mengatasi gejala hidung tersumbat. Dewasa dan anak usia ≥12 tahun: 10 mg tiap 4 jam, dikonsumsi sampai 7 hari. Dosis maksimal 60 mg per hari. Phenylephrine suntik. Phenylephrine sediaan suntik digunakan dalam penanganan syok atau hipotensi yang sangat berat. Dosis phenylephrine suntik akan ditentukan ..., That much phenylephrine 10% could have really messed with your cardiovascular system. Someone please fill me in if there's a diagnostic or therapeutic justification for the amount of drops OP received., Phenylephrine is recognized as the preferred agent of choice even though use in the context of acute ischemic priapism is off label. The AUA/SMSNA provided evidence to support the use of phenylephrine over other sympathomimetic agents. Phenylephrine has been compared to other agents, including epinephrine and ethylephrine, and was found …, Takeaway Pseudoephedrine and phenylephrine are both nasal decongestants but can have different side effects. You can only purchase pseudoephedrine from pharmacy staff and have to show your..., Sinus infections are serious business. Any infection that close to your brain you want checked out. The doctors appointment will cost about 1600yen with your NHI and the meds will be another 1000 yen or so. So go get it treated properly. You're in a first world country with real affordable universal healthcare, use it., Reddit; Print; By Tina Hesman Saey. April 30, 2020 at 5:36 pm. Scientists are investigating a variety of drugs, including ones for anxiety and allergies, that might prevent the coronavirus from ..., Yes, there are allergy medications that are considered safe to take during pregnancy. Experts say that most oral antihistamines, such as Benadryl and Zyrtec, are likely safe during pregnancy. Several nasal steroids, including Rhinocort and Flonase, are also safe to use. Allegra isn’t a first choice to take for allergies during pregnancy due ..., 7,872. Reaction score. 3,859. Oct 19, 2009. #3. I wouldn't be surprised if pseudoephedrine did have some ADHD benefit. Its a sympathomimetic. Other medications which work on the adrenergic system such as clonidine and Venlafaxine have some ADHD benefit. However its not like we have a strong pool of data in this area., Take a syringe and draw up 1 ml of phenylephrine from the vial (vial concentration must be 10 mg/ml) Inject this into a 100 ml bag of NS. Now you have 100 mls of phenylephrine 100 mcg/ml. Draw up some into a syringe; each ml in the syringe is 100 mcg. Dose: 0.5-2 ml every 1-5 minutes (50-200 mcg) No extravasation worries! Mixing …, Phenylephrine is an alpha-agonist - that is, it works at "alpha receptors" in our body. The main effects of these receptors is to cause things to squeeze, like blood vessels, for example. That's how they work on congestion - squeezed vessels = less leaky. Phenylephrine mainly works on the alpha-1 receptors, and that's what their job is - squeezing. , Mar 1, 2022 · DEAR MAYO CLINIC: I have used decongestants over the years when I'm ill, but my doctor recently said that I should be cautious because nonprescription decongestants can have significant side effects. Is this true? ANSWER: While many people rely on nasal decongestants to help ease nasal symptoms of a cold or flu, these medications can sometimes cause […] , Phenylephrine is an over-the-counter nasal decongestant available in 5 mg and 10 mg tablets, as well as an oral solution. It is also available in an injectable form which is only used in an inpatient setting by medical professionals for low blood pressure. Phenylephrine can be purchased without restriction or logging of the purchaser’s ..., Norepinephrine does have a little bit of beta activity, so it can in theory increase HR slightly. The predominant alpha activity causes vasoconstriction, which results in a rise in blood pressure, which will trigger baroreceptors, which will lower the heart rate. In practice, the low beta activity is usually far outweighed by the effect on the ..., I have a few theories that may explain why: The drug would exist already in solution, which might make it easier to separate from inactive ingredients. This would benefit those attempting to produce methamphetamine. The drug itself may damage parts of the nose. It may simply not be very bioavailable intranasally.